Enhanced neurite growth from mammalian neurons in three-dimensional salmon fibrin gels
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چکیده
منابع مشابه
Enhanced neurite growth from mammalian neurons in three-dimensional salmon fibrin gels.
Three-dimensional fibrin matrices have been used as cellular substrates in vitro and as bridging materials for central nervous system repair. Cells can be embedded within fibrin gels since the polymerization process is non-toxic, making fibrin an attractive scaffold for transplanted cells. Most studies have utilized fibrin prepared from human or bovine blood proteins. However, fish fibrin may b...
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The identification of stem-cell-like cancer cells through conventional methods that depend on stem cell markers is often unreliable. We developed a mechanical method for selecting tumorigenic cells by culturing single cancer cells in fibrin matrices of ~100 Pa in stiffness. When cultured within these gels, primary human cancer cells or single cancer cells from mouse or human cancer cell lines g...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2007
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2007.01.008